Overexpression of Candida albicans Secreted Aspartyl Proteinase 2 or 5 Is Not Sufficient for Exacerbation of Immunopathology in a Murine Model of Vaginitis
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The inhibition of Candida albicans secreted aspartyl proteinase by triangular gold nanoparticles
Objective(s): The aim of this study was to synthesize triangular gold nanoparticles, and then to evaluate their capability for inhibition of Candida albicans secreted aspartyl proteinase 2(Sap2).Materials and Methods: To synthesize the nanoparticles, hydrogen tetrachloroaurate and hexadecyl trimethyl ammonium bromide were incubated in presence of Sn(IV) meso-tetra(N-methyl-4-pyridyl) porphine t...
متن کاملthe inhibition of candida albicans secreted aspartyl proteinase by triangular gold nanoparticles
objective(s): the aim of this study was to synthesize triangular gold nanoparticles, and then to evaluate their capability for inhibition of candida albicans secreted aspartyl proteinase 2(sap2).materials and methods: to synthesize the nanoparticles, hydrogen tetrachloroaurate and hexadecyl trimethyl ammonium bromide were incubated in presence of sn(iv) meso-tetra(n-methyl-4-pyridyl) porphine t...
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deployable scissor type structures are composed of the so-called scissor-like elements (sles), which are connected to each other at an intermediate point through a pivotal connection and allow them to be folded into a compact bundle for storage or transport. several sles are connected to each other in order to form units with regular polygonal plan views. the sides and radii of the polygons are...
Inhibition of growth and secreted aspartyl proteinase production in Candida albicans by lysozyme.
Lysozyme (muramidase) is a non-specific, antimicrobial protein ubiquitous in human mucosal secretions such as saliva. Although its antibacterial and antifungal activities are well recognised, there are no data on the specific concentrations necessary to affect the growth of Candida albicans or about the effect of lysozyme on the production of secreted aspartyl proteinase (Sap), a putative virul...
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Vaginal Candida glabrata infections have increased significantly in recent years and are particularly common in women with uncontrolled diabetes mellitus. Efforts to understand the pathogenesis and treatment of this infection have been hindered by the lack of experimental animal models. Before onset of hyperglycemia, nonobese diabetic (NOD) mice inoculated intravaginally with clinical C. glabra...
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ژورنال
عنوان ژورنال: Infection and Immunity
سال: 2017
ISSN: 0019-9567,1098-5522
DOI: 10.1128/iai.00248-17